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HomeValue InvestingBioNTech Replace: What to do now ?

BioNTech Replace: What to do now ?

Disclaimer: This isn’t funding recommendation. PLEASE DO YOU OWN RESEARCH !!!

What a distinction a 12 months could make. Lower than a 12 months in the past, I attempted to enlarge my circle of incompetence by taking a look at BioNTech. This was my abstract again then:

I’ve to confess that some “worry of remorse” performs a job right here. i might deeply remorse to not have invested if this turns into an excellent greater success. Due to this fact I made a decision to take a position “solely” 2% of the portfolio into BioNTech inside my “Long run development bucket” at round 98 EUR/share, reflecting the inherent danger at this stage.

My sport plan can be to carry this at the least 2-3 years and solely contemplate to promote if the inventory drops for no cause by greater than -50% or goes up by greater than +100%.

I count on very optimistic outcomes each, for 2021 and 2022, nonetheless after than, vaccine gross sales will clearly go down after which it must be seen how the most cancers pipeline works out or if they’ll provide you with extra vaccines.

If preliminary pipeline would develop into extra concrete and the valuation nonetheless is sensible, I’d enhance the place in 2 or 3 years from now. In between, the place will inspire me to study extra about mRNA and Biotech generally, which is a pleasant facet impact.

In between the inventory did hit a peak of ~390 EUR in August 2021, I.e. nearly quadrupling from the extent that I purchased earlier than falling again sharply to a degree EUR 150 on the time of writing

I did really promote 30% of my place at costs between 270-300 on the finish of July, getting again my invested cash (earlier than taxes).

The massive query is: What to do now ? 

In such circumstances, I feel step one ought to all the time be to revisit the preliminary assumptions and see what has modified. The case again then was that the assumed earnings of the vaccine plus a future 10% market share within the world “conventional” vaccine market would justify the valuation of again then ~32 bn EUR.

On this case, many issues have modified over the past 12 months and in my view nearly solely to the upside:

Assumption 1: Covid vaccine – 10 bn EUR earnings after tax

Let’s revisit the assumptions I made when i believed that 98 EUR/Share can be an excellent deal:

In line with what I’ve discovered on the web, BioNTech and Pfizer are promoting the vaccine at round 15 USD per shot and that the unique deal was a income cut up of fifty/50. It at present seems like that up to now ~ 1bn doses have been ordered and that for 2022 there are some information articles that as much as 3 bn doses might be required.

So Even when we optimistically assume that BioNTech might really promote 5 bn doses within the subsequent 3-5 years or so, it will “solely” generate as much as 35 bn EUR whole gross sales  and perhaps 10 billion (?) earnings after tax and wouldn’t justify the present valuation. That is the place the underlying mRNA expertise enters the image.

So my assumption was 10 bn EUR whole earnings after tax for the Covid vaccine. In line with the final IR presentation, BioNTech appears to have hit this goal in 2021 alone  by delivering an unbelievable 3 bn doses along with Pfizer.

To maintain issues easy, I assume one other 10 bn in whole earnings and assuming that Covid-19 is not going to be an issue past 2022.

This doesn’t cowl any ongoing  campaigns like for example flu vaccination (see under). Primarily based on these assumptions, Covid-19 provides one other 10 bn EUR in worth in comparison with the initital thesis.

Assumption 2: 10% Market Share vaccine market – 13 bn EUR valuation 

A fast again of the envelope calculation (assuming 25% EBIT margins) would require round 4 bn in annual vaccine gross sales for BioNTech (on high of the one time  Covid-19 vaccine sale) to kind of justify immediately’s valuation. This is able to be lower than 10% of the present world vaccine market which I don’t discover unrealistic as mRNA vaccines appear not solely to be extra environment friendly but additionally faster to fabricate.

My implicit valuation for the vaccine half again then was 13 bn EUR (23 market cap minus 10 bn assumed Covid earnings).

As of immediately, I’d really enhance the valuation right here  due to a number of factors:

1) The uncertainties in regards to the execution capacity of BioNTech and the security of the vaccine are gone. We now know that they’ll produce and distribute enormous quantities at a top quality. This clearly exhibits that their method is far more scalable than Vector vaccines or vaccines with useless viruses. These items simply scales, interval. And the stuff is de facto protected.

2) I feel I’ve additionally underestimated the likelihood, that the vaccine market might really considerably increase. One of many tasks they’re working at is Malaria vaccination which might be a Mega Blockbuster by itself and would increase the worldwide accination enterprise considerably. One other upside might be that as with the flu, Covid-19 vaccinations are required on an ongoing foundation for a while or without end, if we prefer it or not.

Total, I feel one might justify to “spherical this up” to twenty bn EUR together with danger changes. For my part, mRNA is clearly a sport changer for vaccination and as CureVac and the Chinese language efforts present, it’s not really easy to repeat and paste the expertise. There appear to be some very severe obstacles to entry.

This leaves us with a price of 20+20 bn = 40 bn EUR worth which, by coincidence (I swear, that is was not meant), is sort of much like immediately’s market cap.

So once more, we’re at a scenario, the place based mostly on my assumptions, the remainder of the pipeline (Most cancers, and so forth.) comes principally “without cost”.

“Upside Optionality” 

For my part, there may be a number of extra “upside Optionality” for BioNTech on high of what I’ve described above::

a) Though I actually hope that Covid is over, there may be nonetheless a small chance that there could be new variants that require a brand new vaccine and the entire vaccination effort has to start out once more. I do suppose it’s a small chance however nonetheless BioNTech is a “tail hedge” for these situations.

b) There would possibly nonetheless be the possibility that they may attain a cope with China. As Covid-19 isn’t going away and the Chinese language vaccine very ineffective, I nonetheless see an opportunity for BioNTech to promote just a few hundred million )or just a few billion) doses to China. China won’t be able to carry up its “Zero Covid” coverage without end.

c) With the success of the vaccine (and the cash) they’ll now select between the very best cooperation companions and/or do M&A to broaden or speed up their pipeline. They made already two fascinating acquisitions with Phagomed and KITE

d) I additionally suppose that they haven’t any issues in attracting the very best and brightest to the corporate. They appear to have elevated their R&D employees by 40% in the previous few months.

Even after considering laborious, I haven’t recognized something actually damaging apart from “excessive anti-vax” actions inside a small a part of the society.

Valuation of the Pipeline

As a technical level, with extra money on its Steadiness sheet and all different assumptions held equal, the chance of executing the pipeline with out shareholder dilution cleary will increase. This in flip technically will increase the worth of the pipeline. Nevertheless as I’m not capable of worth the Most cancers pipeline, I can’t account for this impact.


There are after all additionally a number of dangers, simply to say just a few:

  • a surprise remedy for Covid-19
  • a number of opponents handle to develop equal or higher mRNA vaccines
  • The Chinese language are capable of steal the “secret sauce”
  • there are extreme damaging long run results of mRNA vaccines
  • They allocate capital badly

However, as a abstract, I truthfully do suppose that BioNTech at 150 EUR per share in 2022 is an identical and even higher deal than at 98 EUR in 2021.


As outlined above, I do suppose that BioNTech represents at the least the identical enticing deal at 150 EUR in 2022 than at 98 EUR in 2021 as a number of issues have gone higher than I anticipated again then.

Nevertheless Mr. Market can do something within the subsequent few months /years. Typically, share costs overshoot in each instructions.

So my sport plan hasn’t modified that a lot: I’ll hold my remaining place and watch how issues develop. Promoting now doesn’t make sense basically, and “Buying and selling round/throughout the place” is clearly not my power.

The reply to the preliminary query “What to do now ?” at the least for me is obvious: Observe and do nothing.

Disclaimer: This isn’t funding recommendation. PLEASE DO YOU OWN RESEARCH !!!



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